Genetic Analysis: An Integrated Approach (3rd Edition) By Mark F. Sanders and John L. Bowman

Free download Genetic Analysis: An Integrated Approach (3rd edition) written by Mark F. Sanders and John L. Bowman in pdf.

This third edition, like its predecessors, carries the unique subtitle An Integrated Approach. The phrase embodies our pedagogical approach, consisting of three principles: (1) to integrate problem solving throughout the text—not relegating it to the ends of chapters—and consistently to model a powerful, three-step problem-solving approach (Evaluate, Deduce, and Solve) in every worked example; (2) to integrate an evolutionary perspective throughout the book; and (3) to integrate descriptions of Mendelian genetics with molecular genetics and genomics so as to demonstrate the value of each of these different approaches for investigating the same basic sets of observations. In this edition, we adhere to and strengthen the integration that has resonated strongly with instructors and students.

As was the case in our previous editions, our aim above all is to assist the student by making the learning of genetics easier, more interesting, and more effective. Thus, three specific goals have driven this revision, and each is supported by new features that help accomplish it. Goal 1 is to provide more interesting, real-world applications of genetics.

We have addressed this goal by writing five “Application Chapters” that each highlight a particular applied topic in human genetics. Goal 2 is to make the job of learning the details of genetics easier. We have addressed this goal by writing “Caption Queries” to accompany chapter figures and by providing a new feature, titled “Preparing for Problem Solving,” at the end of each chapter.

Goal 3 is to facilitate group work and discussion of genetics problems and concepts among classmates. We have addressed this goal in part through the Caption Queries and in part by providing a new category of chapter problems, called “Collaboration and Discussion,” that are specifically designed to be tackled in groups.

Contents

• The Molecular Basis of Heredity, Variation, and Evolution
• Transmission Genetics
• Cell Division and Chromosome Heredity
• Gene Interaction
• Genetic Linkage and Mapping in Eukaryotes
• Genetic Analysis and Mapping in Bacteria and Bacteriophages

Application A: Human Hereditary Disease and Genetic Counseling

• DNA Structure and Replication
• Molecular Biology of Transcription and RNA Processing
• The Molecular Biology of Translation

Application B: Human Genetic Screening

• Eukaryotic Chromosome Abnormalities and Molecular Organization
• Gene Mutation, DNA Repair, and Homologous Recombination
• Regulation of Gene Expression in Bacteria and Bacteriophage
• Regulation of Gene Expression in Eukaryotes
• Analysis of Gene Function by Forward Genetics and Reverse Genetics

Application C: The Genetics of Cancer

• Recombinant DNA Technology and Its Applications
• Genomics: Genetics from a Whole-Genome Perspective
• Organellar Inheritance and the Evolution of Organellar Genomes
• Developmental Genetics
• Genetic Analysis of Quantitative Traits
• Population Genetics and Evolution at the Population, Species, and Molecular Levels

Application D: Human Evolutionary Genetics
Application E: Forensic Genetics

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