Free download Biochemistry (7th edition) written by Reginald H. Garrett & Charles M. Grisham in pdf.
According to the writers, “Scientific understanding of the molecular nature of life is growing at an astounding rate. Significantly, society is the prime beneficiary of this increased understanding. Cures for diseases, better public health, remedies for environmental pollution, and the development of cheaper and safer natural products are just a few practical benefits of this knowledge.
In addition, this expansion of information fuels, in the words of Thomas Jefferson, “the illimitable freedom of the human mind.” Scientists can use the tools of biochemistry and molecular biology to explore all aspects of an organism—from basic questions about its chemical composition, through inquiries into the complexities of its metabolism, differentiation, and development, to analysis of its evolution, and even its behavior.
New procedures based on the results of these explorations lie at the heart of the many modern medical miracles. Biochemistry is a science whose boundaries now encompass all aspects of biology, from molecules to cells, to organisms, to ecology, and to all aspects of health care.
This seventh edition of Biochemistry embodies and reflects the expanse of this knowledge. We hope that this new edition will encourage students to ask questions of their own and to push the boundaries of their curiosity about science.”
This biochemistry textbook is designed to communicate the fundamental principles upon which all life is based to students encountering biochemistry for the first time. We aim to bring an appreciation of biochemistry to a broad audience that includes undergraduates majoring in the life sciences, physical sciences, or premedical programs as well as medical students and graduate students in the various health sciences for whom biochemistry is an important route to understanding human physiology.
To make this subject matter more relevant and interesting to all readers, we emphasize, where appropriate, the biochemistry of humans.
Contents
Part I Molecular Components of Cells
- The Facts of Life: Chemistry Is the Logic of Biological Phenomena
- Water: The Medium of Life
- Thermodynamics of Biological Systems
- Amino Acids and the Peptide Bond
- Proteins: Their Primary Structure and Biological Functions
- Proteins: Secondary, Tertiary, and Quaternary Structure
- Carbohydrates and the Glycoconjugates of Cell Surfaces
- Lipids
- Membranes and Membrane Transport
- Nucleotides and Nucleic Acids
- Structure of Nucleic Acids
- Recombinant DNA, Cloning, Gene Editing, and Synthetic Biology—An Introduction
Part II Protein Dynamics
- Enzymes—Kinetics and Specificity
- Mechanisms of Enzyme Action
- Enzyme Regulation
- Molecular Motors
Part III Metabolism and Its Regulation
- Metabolism: An Overview
- Glycolysis
- The Tricarboxylic Acid Cycle
- Electron Transport and Oxidative Phosphorylation
- Photosynthesis
- Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway
- Fatty Acid Catabolism
- Lipid Biosynthesis
- Nitrogen Acquisition and Amino Acid Metabolism
- Synthesis and Degradation of Nucleotides
- Metabolic Integration and Organ Specialization
Part IV Information Transfer
- DNA Metabolism: Replication, Recombination, and Repair
- Transcription and the Regulation of Gene Expression
- Protein Synthesis
- Completing the Protein Life Cycle: Folding, Processing, and Degradation
- The Reception and Transmission of Extracellular Information
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