Free download Concepts of Genetics (12th edition) written by William S. Klug, Michael R. Cummings, Charolette A. Spencer, Michael A. Palladino and Darrell J. Killian in pdf.
Concepts of Genetics emphasizes the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. This bestselling text continues to provide understandable explanations of complex, analytical topics and recognizes the importance of teaching students how to become effective problem solvers.
Six Special Topics in Modern Genetics mini chapters concisely explore cutting-edge, engaging, and relevant topics.
The 12th edition has been heavily updated throughout, including a reorganization and expansion of coverage of gene regulation in eukaryotes. This expansion reflects our growing knowledge of the critical roles RNA and epigenetics play in regulating gene activity.
With the rapid growth of our understanding of genetics and the ongoing introduction of powerful tools that can edit genes and genomes, it’s important to encourage students to confront ethical issues and consider questions that arise in the study of genetics.
Contents
Part I: Genes, Chromosomes, and Heredity
- Introduction to Genetics
- Mitosis and Meiosis
- Mendelian Genetics
- Extensions of Mendelian Genetics
- Chromosome Mapping in Eukaryotes
- Genetic Analysis and Mapping in Bacteria and Bacteriophages
- Sex Determination and Sex Chromosomes
- Chromosome Mutations: Variation in Number and Arrangement
- Extranuclear Inheritance
Part II: DNA: Structure, Replication, and Organization
- DNA Structure and Analysis
- DNA Replication and Recombination
- DNA Organization in Chromosomes
Part III: Gene Expression and Its Regulation
- The Genetic Code and Transcription
- Translation and Proteins
- Gene Mutation, DNA Repair, and Transposition
- Regulation of Gene Expression in Bacteria
- Transcriptional Regulation in Eukaryotes
- Post-transcriptional Regulation in Eukaryotes
- Epigenetics
Part IV: Genetic Technology and Genomics
- Recombinant DNA Technology
- Genomic Analysis
- Applications of Genetic Engineering and Biotechnology
Part V: Genetic Analysis of Organism and Populations
- Developmental Genetics
- Cancer Genetics
- Quantitative Genetics and Multifactorial Traits
- Population and Evolutionary Genetics
Special Topics in Modern Genetics
- CRISPR and Genomic Editing
- DNA Forensics
- Genomics and Precision Medicine
- Genetically Modified Foods
- Gene Therapy
- Advances in Neurogenetics: The Study of Huntington Disease
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