Free download Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry (12th edition) written by John M. Beale and John H. Block in pdf.
For 6 decades, Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry has been a standard in the literature of medicinal chemistry. Generations of students and faculty have depended on this textbook not only for undergraduate courses in medicinal chemistry but also as a supplement for graduate studies. Moreover, students in other health sciences have found certain chapters useful.
The current editors and authors worked on the 12th edition with the objective of continuing the tradition of a modern textbook for undergraduate students and also for graduate students who need a general review of medicinal chemistry. Because the chapters include a blend of chemical and pharmacological principles necessary for understanding structure–activity relationships and molecular mechanisms of drug action, the book should be useful in supporting courses in medicinal chemistry and in complementing pharmacology courses.
The 12th edition follows in the footsteps of the 11th edition by reflecting the dynamic changes occurring in medicinal chemistry. With increased knowledge of the disease process and the identification of the key steps in the biochemical process, the chapters have been updated, expanded, and reorganized. At the same time, to streamline the presentation of the content, some topics were combined into existing chapters.
Contents
- Introduction
- Drug Design Strategies
- Metabolic Changes of Drugs and Related Organic Compounds
- Biotechnology and Drug Discovery.
- Immunobiologicals
- Anti-infective Agents
- Antimalarials
- Antibacterial Antibiotics
- Antiviral Agents
- Antineoplastic Agents
- Agents for Diagnostic Imaging
- Central Nervous System Depressants
- Central Dopaminergic Signaling Agents
- Anticonvulsants
- Central Nervous System Stimulants
- Adrenergic Agents
- Cholinergic Drugs and Related Agents
- Drugs Acting on the Renal System
- Cardiovascular Agents
- Hormone-Related Disorders: Nonsteroidal Therapies
- Agents Treating Bone Disorders
- Anesthetics
- Histamine and Antihistaminic Agents
- Analgesics
- Steroid Hormones and Therapeutically Related Compounds
- Prostaglandins, Leukotrienes, and Essential Fatty Acids
- Proteins, Enzymes, and Peptide Hormones
- Vitamins
- An Introduction to the Medicinal Chemistry of Herbs
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