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Aldol Reaction – Mechanism and Stereochemistry
Reaction of aldehydes or ketones to give β-hydroxy carbonyl compounds. The addition of the α-carbon of an enolizable aldehyde or ketone 1 to the carbonyl group of a second aldehyde or ketone 2 is called the aldol reaction.1,2 It is a versatile method for the formation of carbon–carbon bonds, and is frequently used in organic […]